Los Angeles dermatologist Ava Shamban calls Ozempic’s Hollywood entrance “the hottest thing since, oh I don’t know, pasteurization and the bikini wax!” The injectable diabetes drug has turn into topic number one amongst moneyed weight watchers from Malibu to Madison Avenue and just about all over the place in between. “It went from ‘Have you heard of it?’ to ‘Who is doing it?’ and moving into who-is-not-doing-it territory in certain circles,” Shamban says. The attract is powerful: “Who doesn’t want to have better blood sugar control, enhanced longevity, increased memory, diminished brain fog and weight loss all at the same time?”

The diabetes drug has turn into a sizzling subject amongst moneyed weight watchers from Malibu to Madison Avenue.

But it’ll price you. Those prepared to prick and pay for entry to Ozempic for weight reduction are shelling out upwards of $1,500 a month to provide themselves semaglutide injections within the tummy and tush, and developing with all types of causes they’re again of their slip attire, few of which contain admitting to truly taking the drug. (That’s in individual…TikTok is one other story. See #MyOzempicJourney). But the slimming facet impact shouldn’t be the one factor that’s a part of the dialog.

Ozempic, a semaglutide drug by Novo Nordisk, has been confirmed to manage insulin, suppress urge for food, and decrease the chance of cardiovascular occasions for diabetic sufferers. (Another model, Wegovy, is prescribed for sufferers with weight problems. Mounjaro, a tirzepatide injection for diabetes, can also be on the rise, as are unbranded variations made by compounding pharmacies are repeatedly prescribed for many who need to shed extra pounds however can’t abdomen the funds not lined by insurance coverage). Over the previous couple of months, its use has turn into so ubiquitous that it has been linked with drug shortages for many who are medically dependent, the troubling return of development tales about heroin-chic thinness, and, in keeping with one distinguished physician, dermatologist Paul Jarrod Frank, an uptick in what he calls “Ozempic face.”


“In my 25 plus years in medicine there have been only two other drugs that have been on the tip of everyone’s tongue before this: Botox and Viagra,” says Frank. “Just like Botox changed the way we look at wrinkles and Viagra changed the way we look at sex,” Ozempic, he says, is altering the best way we take into consideration weight reduction.

Only two different medication have been on the tip of everybody’s tongue earlier than this: Botox and Viagra.

Typically any beauty affected person, significantly as they become old, will expertise facial sagging with weight reduction. “They say their body is in great shape but they feel like their face is sagging,” Frank says, mentioning that weight reduction over the age of fifty comes with aesthetic penalties he likens to letting the air out of a balloon. “It takes a certain category of filling to fix that, and that’s volume restoration,” Frank provides. Rather than going after particular person wrinkles, he’s utilizing biostimulatory fillers like Radiesse and Sculptura to restructure the face as an entire, including quantity whereas stimulating collagen.

Washington, DC dermatologist Tina Alster, who’s behind most of the faces we see on cable information and Capitol Hill, reviews an uptick in remedy requests from sufferers whose faces have turn into gaunt after Ozempic and Wegovy. “I have had to increase the amount and frequency of filler injections and laser resurfacing procedures to counteract associated facial wrinkles,” she reviews. “I’ve had a couple of patients who also report hair loss for which I have been performing PRP (platelet-rich plasma) scalp injections.” New York City dermatologist Pat Wexler been using a mix of therapies to work in opposition to sinking and sagging: Radiesse injections and Ulthera therapies so as to add quantity and stimulate collagen and elastic tissue; and Sofwave for superficial strains.

Shamban explains that the pace with which weight reduction is going on on Ozempic may compound the problem, not only for the face, however the physique as properly. “When volume losses are extensive in short time periods, the structural skin fibers and dermal network do not have the right amount of time to process the adipose tissue loss with any ‘snap back’ and tighten up as it might with a slower weight loss.”

Weight loss previous 50 comes with aesthetic penalties akin to letting the air out of a balloon.

At what level do the medical and beauty negative effects outweigh the results themselves? When it involves weight reduction, there’s a excessive threshold for ache. “I am concerned that, in addition to the common headaches, fatigue, nausea, and diarrhea experienced by most people on the medication, there are growing reports of associated serious side effects including vision changes and organ inflammation (eg, pancreatitis),” reviews Alster.

Patients experiencing beauty negative effects from Ozempic is perhaps confronted with greater than a needle or laser at their subsequent go to to the dermatologist—in the event that they’re fortunate. “When I see a patient getting thinner and thinner and more hollow, they lose perception of what they really look like,” Wexler says. “I feel like it’s my responsibility to tell them they’ve reached their limit and back off. It is addictive. It’s not an opiate, but anything—even shopping—can be addictive.” She has cautioned sure sufferers who’ve gone too far to drag again on their dosages.

“The advertising is seductive. Going on it is seductive,” Wexler says. “It’s my duty as a physician to point out problems with any treatment, whether it’s something I gave them or not.”


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