Nizoral is an especially widespread dermatologist really helpful ketoconazole 1% primarily based dandruff shampoo. It additionally has modest hair development properties.

As of December 2023, Nizoral has virtually 88,000 critiques on Amazon, with a mean ranking of 4.6 out of 5 stars. It prices simply $14.28 for the smaller 7 fl oz (200 ml) bottle. This is a really inexpensive worth when in comparison with different main dandruff shampoos. The 14 fl oz (400 ml) bottle is at present priced at $27.57 on Amazon.

A November 2023 examine from India successfully developed and tested a novel anti-dandruff shampoo included with ketoconazole-coated zinc oxide nanoparticles. The researchers needed to enhance on present ketoconazole (KTZ) primarily based shampoos with weak pores and skin dermis absorption and permeability. The ready nanoparticles confirmed enhanced exercise in opposition to Malassezia furfur in comparison with common KTZ (1%).

A May 2022 examine from Brazil discovered that ketoconazole shifts the scalp skin lipid profile, impacts Malassezia lipid metabolism and favors biotin-producing micro organism. Biotin improves inflammatory situations.

Nizoral Shampoo

Nizoral Shampoo 1% Anti-Dandruff.

Nizoral shampoo (1%) is without doubt one of the highest rated and reviewed anti-dandruff shampoos that you could purchase and not using a prescription. I rank it as one of many 10 finest hair loss shampoos on the earth. You should purchase it at most shops, together with Walmart (4,500 critiques), Target (4,700 critiques) and CVS (3,700 critiques).

Nizoral A-D Anti-Dandruff Shampoo with ketoconazole 1%, is consistently rated as probably the greatest merchandise to counter dandruff, scalp itching, flaking and fungus. We all shed thousands and thousands of lifeless pores and skin cells each single day. However, some individuals have extreme pores and skin turnover on the scalp, resulting in dandruff.

Nizoral (usually misspelled as Nizarol) can enhance psoriasis signs, scaly scalp pores and skin, yeast infections and even foot fungus. Some studies counsel it might probably additionally profit fungal zits, though facial utilization just isn’t really helpful.

Nizoral 2% Dandruff Shampoo.
Nizoral 2% Ketoconazole Medicated Shampoo.

A small bottle of this extremely rated antifungal anti-inflammatory product will final for a lot of months. Note that Nizoral 2% shampoo is available in a pink bottle and is a unique product. The Nizoral 1 % is an over-the-counter product, whereas the medicated 2 % requires a prescription within the US.

Also value noting, Nizoral shampoo may also help scale back hair loss to a reasonable extent because of its anti-androgenic properties. See the research listed on the finish of this put up that assist this level. Other widespread hair loss shampoos embrace Revivogen and Shiseido Adenovital.

Ketoconazole 1%: The Active Ingredient

The record of elements in Nizoral will be discovered within the FDA label pdf. The key energetic ingredient is ketoconazole 1%. Ketoconazole (abbreviated KCZ or KTZ) additionally has some anti-androgenic properties.

To date, solely two medicine with very totally different mechanisms of motion have been accredited by the US FDA to deal with hair loss: Finasteride (Propecia) and Minoxidil (Rogaine).

Nizoral Shampoo Ingredients.
Nizoral shampoo ingredient record. Includes Ketoconazole 1% to battle dandruff.

However, Ketoconazole (the energetic ingredient in Nizoral shampoo) additionally has some hair development advantages. It is an imidazole anti-fungal agent that counters dandruff and scalp irritation.

Ketaconazole will doubtless by no means be formally accredited to deal with hair loss, as a result of its producer is unlikely to ever file for approval. With gross sales of Nizoral already going robust globally, it’s most likely not value going by all of the rigorous costly medical trials to get little additional benefit.

Ketoconazole is an artificial drug that’s used to deal with fungal infections. In explicit, the drug flushes out Malassezia (previously often known as Pityrosporum) yeast fungus. Malassezia has been implicated in issues equivalent to dandruff and seborrheic dermatitis. The latter results in clogged hair follicles.

Other names for related fungal infections and overgrowth of the scalp embrace Pityriasis Versicolor, Pityrosporum Ovale and Malassezia Furfur. Skin situations equivalent to tinea and ringworm can also profit from this product.

Ketoconazole was initially accessible in pill kind, however has since additionally been developed into topical varieties equivalent to lotions, lotions and shampoos. Note that oral ingestion of ketoconazole can result in serious side effects equivalent to liver injury in some sufferers. However, topical cream and ketoconazole shampoo utilization have usually not been linked to such uncomfortable side effects.

My Nizoral Experiences for Scalp Itching

A big proportion of hair loss victims appear to additionally get itchy and dry scalp situations, together with dandruff and seborrheic dermatitis. I’m a kind of, though the severity and frequency of my signs is reasonable.

Some years in the past, I began utilizing Nizoral 1% anti dandruff shampoo for my itchy infected scalp as an alternative of different common shampoos. I used to be completely amazed at its effectiveness in fully eliminating my scalp itching and dandruff for a minimum of a day or two after every utility. My hair appeared higher and more healthy, and it appeared like my each day hair shedding fee additionally declined.

Update: December 2023 — These days I exploit Head & Shoulders medicated, though simply as soon as each three weeks. Nizoral was making my hair a bit too dry and lifeless.

There is a few proof that ketoconazole blocks the synthesis of dihydrotestosterone within the scalp and acts as an antagonist of the androgen receptor (see record of research on the backside of this put up).

Nizoral Conditioner

Nizoral now additionally sells a preferred deep moisturizing hair conditioner product. It is meant to counter the drying results of Nizoral shampoo.

The conditioner is freed from sulfates, parabens, synthetic fragrances and dyes. Among the important thing elements within the conditioner (which comprises seven moisturizers) embrace:

  • Shea Butter.
  • Jojoba Seed Oil.
  • Peppermint Oil.
  • Tea Tree Leaf Oil.

How usually Should you utilize Nizoral Shampoo?

I might advocate utilizing Nizoral shampoo not more than twice every week with a purpose to stop extreme pores and skin dryness. You additionally are not looking for your scalp microflora and fungi to develop into resistant to the results of ketoconazole. Overuse will make your scalp pores and skin excessively dry and make your hair brittle. I might recommending rotating between a number of totally different merchandise among the many finest dandruff shampoos accessible.

When you do shampoo with Nizoral, be sure that to maintain it in your scalp for a minimum of 3-4 minutes after lathering and earlier than rinsing. Some individuals advocate rinsing hair in chilly water slightly than scorching water within the bathe. The former prevents extreme moisture loss and pores and skin drying out.


In 2012 or so, it appeared like US drug shops and pharmacies equivalent to Walmart, Walgreens and CVS stopped carrying Nizoral shampoo, a minimum of in the case of the most well-liked blue bottle selection (see photograph additional under). I believed this was due to the warnings associated to uncomfortable side effects from taking oral ketoconazole. I later discovered that the issues with availability had been as a result of shampoo’s producer having manufacturing points at its predominant vegetation, slightly than any points associated to uncomfortable side effects.

Luckily, I had adequate provides to final me for some time, because you solely want a small quantity of Nizoral shampoo to make an enormous distinction. Most individuals don’t want to make use of it greater than twice every week. However, this scarcity continued in 2013 and I then needed to pay a major premium to purchase it from a vendor on ebay. Lots of people took benefit of this case by promoting their surplus Nizoral inventory on-line in 2012 and 2013.

In 2014, Nizoral got here again in the marketplace and the shortages lastly ended. No provide points have occurred since that point. You can learn quite a few favorable critiques of Nizoral on-line.

Nizoral Side Effects

As lengthy as you aren’t taking Nizoral (i.e., Ketoconazole) orally, uncomfortable side effects are normally restricted and transient. The predominant uncomfortable side effects that may come up from utilizing Nizoral shampoo embrace:

  • Itchy scalp.
  • Dry scalp pores and skin.
  • An unnatural hair texture and really feel.
  • Rashes, hives and different allergic reactions.
  • Red infected eyes in case the product unintentionally will get in there.

Ketoconazole and Hair Loss Studies

You can discover many research that counsel Nizoral causes a discount in hair loss and thinning. Ketoconazole has anti-androgenic properties that might sluggish the development of androgenetic alopecia (aka male sample baldness). Below are some such research so as of oldest to most up-to-date:

In June 2018, Germany’s Stada acquired Nizoral from Johnson & Johnson. For more moderen info, see Nizoral’s official Instagram page.

This article was initially written on January 26, 2019. Updated on December 12, 2023.

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