Note that the more and more in style low-dose oral Minoxidil for hair loss (taken through ingesting capsules or tablets) acts a bit in a different way in comparison with sublingual Minoxidil (taken through dissolving beneath the tongue). Read the underside half authentic model of this put up for extra particulars.
Sublingual Minoxidil for Hair Loss Updates
Update: February 2023 — A HRN discussion board member named “Viney” is posting excellent details with pictures of his hair regrowth from sublingual Minoxidil and Dutasteride. He sees a dermatologist at Sinclair Dermatology (Melbourne, Australia).
Update: January 2023 — I posted one thing on Twitter about sublingual Minoxidil probably being more effective than oral Minoxidil. Below are the attention-grabbing responses from Dr. Corralo and Dr. Bhoyrul:
Update: December 2022 — Also see this thread on Twitter in relation to the identical topic.
Update: September 2021 — A scientific trial of 40 female and male sufferers receiving sublingual Minoxidil (SM) for androgenetic alopecia simply ended. Per the summary, SM produced a dose-dependent improve in imply terminal hair depend of the frontal and vertex scalp and an enchancment in hair density. There was no have an effect on on blood strain. Quote from reviewer Dr. Mirmirani:
“The authors suggest that sublingual Minoxidil (SM) may have better bioavailability and fewer hemodynamic effects by avoiding first-pass liver metabolism. Although the data in this study are positive, it will take more to convince me that it is significantly better than oral Minoxidil (OM). Very few of my patients on low-dose OM for hair loss discontinue the medication due to side-effects. The other consideration is cost. OM it is an inexpensive, generic drug, that is covered by medical benefits.”
Update: March 2021 — An glorious video presentation on sublingual Minoxidil from Dr. Bevin Bhoyrul from Sinclair Dermatology:
Update: July 2020 — Also from Sinclair Dermatology comes a case series report of 64 sufferers taking sublingual Minoxidil (0.45 mg per day) for sample hair loss.
April 9, 2018
Sinclair Dermatology
Earlier at this time, a reader named Chris posted a really attention-grabbing video about a new hair loss treatment from Australia that entails placing some sort of dissolvable listerine-style strip beneath the tongue. Chris requested me for my opinion about this remedy.
At first, I believed that this appeared like an apparent rip-off for the reason that title of the video contains the phrase “breakthrough” in it. Moreover, the video doesn’t even point out what substances are within the sublingual strip or patch itself.
However, for the reason that well-known Australian dermatologist Dr. Rodney Sinclair seems within the video, I made a decision to conduct additional analysis. Dr. Sinclair (related to “The Hairy Pill“) is an extremely well respected researcher in the hair loss world. In the above video, he is honest and clearly says that this treatment will not bring back hair in totally bald scalps.
Having said that, so far it seems that the results from this treatment on people who have moderate levels of balding have been very positive. And this got me curious about what magic concoction was in the strip itself?
Clinical Trial for Sublingual Minoxidil
I did not have to conduct much further research to figure out what this new potential breakthrough hair loss cure entailed. On Dr. Sinclair’s blog, the latest post from today discusses a new clinical trial they are conducting that is recruiting both men and women. Volunteers will be treated with low-dose oral Minoxidil that will be given as a sublingual tablet (which will dissolve under the tongue).
I would not be surprised if the tablet is actually the strip/patch that was shown in the video I posted earlier. It would be very uncomfortable to put an actual tablet underneath the tongue and wait for it to dissolve, unless the dissolution happened very rapidly. On the other hand, a strip would be much easier to keep in place underneath the tongue for a longer period of time.
I discussed oral Minoxidil for hair loss in detail last year. While I often use topical Minoxidil foam, I would not take the oral version as I do not want more body hair as a potential side effect. However, oral Minoxidil clearly seems to be a superior option to topical Minoxidil when it comes to hair growth benefits. Partly due to the sulfotransferase issue.
If you live in Australia or in the nearby vicinity, perhaps it is worth volunteering for these trials. Today I finally learnt the definition of “sublingual”.
Also make certain to learn my put up on additional energy Minoxidil 15 p.c for different options to common dosage store-bought Minoxidil foam.
