January 10, 2023

Humans Still Have the Genes for a Full Coat of Body Hair

Several readers lately despatched me hyperlinks to new findings in relation to human and mammalian hair genes. Apparently, human nonetheless have the genes for a full coat of hair (or fur), which isn’t stunning to me. I’ve no scarcity of physique hair, though the hair on my again is usually fantastic non-terminal hair. Men with extreme physique hair are inclined to go bald extra extensively and at a youthful age.

The scientists (Dr. Nathan Clark, Dr. Amanda Kowalczyk and Dr. Maria Chikina) behind this latest work state that:

“It could eventually lead to new ways to recover hair after balding”.

This research was a first-of-its-kind comparability of genetic codes from so many animals (62). The analysis staff surveyed 19,149 genes and 343,598 regulatory areas throughout the mammalian species. It is kind of extraordinary that so many various mammals (together with people) have used completely different methods to deactivate a typical set of genes. All in an effort to shed their hair and fur.

Make certain to additionally learn my posts on CRISPR and on gene modification by way of NgAgo.

March 1, 2016

Hair Related Genes

A significant discovery was simply introduced at present and extensively coated by the worldwide media  (e.g., see the BBC article, Telegraph abstract and Washington Post article).

The essential Nature Communications human hair genome diagram pasted beneath is kind of a visible.

Hair genes. Genetic hyperlink for a monobrow. Nature 531, 143 (2016).

Key genes for gray hair, monobrows, hair thickness, hair form and extra had been found by a staff led by Dr. Kaustubh Adhikari. The international media has largely centered on the gray hair problem.

Interestingly, the staff did all their analysis in Latin America, the worldwide hotspot of human genetic variety as a result of area’s giant populations of Caucasoids/Whites, Natives/Indians and Negroids/Blacks. Brazil can be house to the biggest inhabitants of Japanese (Mongoloids) exterior of Japan. An spectacular 6,630 volunteers had been studied. Key discoveries:

  • The IRF4 gene’s presence appears correlated with an earlier lack of hair colour. Also see my put up on the remedy for gray hair.
  • Unibrows (or monobrows) are related to a gene known as PAX3.
  • The EDAR gene is related to straight scalp hair and sparse facial hair — each of that are widespread options in East Asian males.
  • The PRSS53 gene is linked to curly hair.

Some fascinating quotes:

“The finding could mean that changing hair or eye color could be possible without using dyes. It would simply be a matter of taking a drug which changed the expression of certain genes to alter appearance, turning blondes into brunettes or preventing grey hair.”

“Preventing grey hair is a possibility and even reversing grey hair might not be impossible. Once we know more about the pigmentation process, and all the genes involved it should be easy to find a protein or enzyme to up-regulate or down-regulate the activity.”

One fascinating implication for the cosmetics trade is that hair look might sooner or later be modified as it’s fashioned beneath the pores and skin. As against after exiting from the pores and skin floor, which is the present norm with hair dyes and hair straighteners.


Source by [author_name]

Leave a comment

Your email address will not be published. Required fields are marked *