Is Ozempic Really a ‘Miracle Drug’ for Weight Loss? We Spoke to the Experts

It was accredited by the FDA in 2017 for treating diabetes. Now, Ozempic, an injectable drug made with an energetic ingredient known as semaglutide, has turn into a pop-culture phenomenon.

Variety reports that it’s so prevalent in Hollywood that trade individuals “are quietly singing the drug’s praises on Signal, the encrypted messaging app mostly used for confidential conversations.” Elon Musk has admitted to taking it. The hashtag #Ozempic has 1.3 billion views on TikTok. That’s proper — billion.

With a lot enthusiasm, pharmaceutical firms are keen to satisfy the demand: Wegovy — which has the identical energetic ingredient as Ozempic — and Mounjaro — a diabetes drug with a unique energetic ingredient however comparable weight reduction results — are two comparable medicines at present available on the market, and there are extra within the works, in keeping with the New York Times.

So, what ought to the typical individual make of all this? Is Ozempic a miracle drug that may enable you lose cussed kilos? Or is all this hype normalizing the concept of taking diabetes treatment when you do not even have diabetes? And what concerning the negative effects? Here’s what you want to know, in keeping with consultants.


How Ozempic Works


“Ozempic primarily impacts hunger and satiety. GLP-1, the protein this drug emulates, stimulates parts of the brain controlling hunger, making one feel less inclined to eat,” in keeping with Dr. Brad Dieter, PhD, MS, Chief Operating Officer at Macros Inc. “In addition, Ozempic also increases gastric emptying time, which also contributes to weight loss by increasing satiety. Gastric emptying time is the time period required by the food to pass through the gastrointestinal tract. So when the food moves through the tract slowly, it maintains one’s satiety for a long time and prevents one from overeating,” provides Edibel Quintero, an RD and medical advisor at HealthInsider

The preliminary concept behind Ozempic was treating diabetes by managing blood sugar. Weight loss occurred to be a facet impact, which paved the best way for the drug’s present reputation as a weight reduction instrument. So, does it work? The brief reply is sure. The longer reply comes with a number of caveats.

Research on using once-weekly semaglutide in overweight or obese adults with out diabetes confirmed that, when mixed with way of life intervention, the drug was related to “substantial, sustained, clinically relevant mean weight loss of 14.9%, with 86% of participants attaining at least 5% weight loss.” Lifestyle intervention is a vital distinction — the A-listers taking Ozempic are doubtless not feasting on McDonald’s and skipping the gymnasium.

The Ozempic craze is not directly highlighting a shifting paradigm within the vitamin world over the previous few years: the concept that weight reduction is solely about energy and out. 

“Everybody is different and weight loss is not always as simple as calories in, calories out,” says Dr. Sudeep Singh, associate at Apprize Medical. “While how much we eat is obviously a huge part of that equation, underlying medical problems should also be addressed at the same time.” 

Dr. Singh cites elements equivalent to excessive ranges of stress and hormonal imbalances as a few of the issues that affect somebody’s potential to drop extra pounds. Blood sugar administration is a kind of elements, and that’s the place a instrument like Ozempic can help.


Is Ozempic Safe for Losing Weight?


That stated, it doesn’t come with out potential negative effects. “While Ozempic has shown potential in weight loss, it’s accompanied by significant side effects. Studies highlight alarming rates of nausea, abdominal pain, vomiting, dizziness, and even heart palpitations among users, far surpassing those on placebo,” in keeping with Dieter.

A CNN article featured the tales of two ladies who had been prescribed Ozempic and ended up experiencing a uncommon but severe facet impact — abdomen paralysis. Another lady featured within the article had been coping with frequent vomiting even after being off the treatment for over a yr — she needed to take a go away of absence from work.

Granted, these tales don’t characterize the vast majority of circumstances, however they’re a sober reminder that simply because one thing is common doesn’t imply that it must be taken frivolously.

RELATED: The Best Ways to Lose Fat

There are additionally contraindications.

“People with pancreatitis, medullary thyroid carcinoma, and endocrine and kidney problems should not use Ozempic at any cost,” warns Quintero. “Similarly, Ozempic is not safe for pregnant and breastfeeding women.”

Keep in thoughts that Ozempic “is approved by the FDA for adults with type 2 diabetes to lower blood sugar, along with diet and exercise, and reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes and known heart disease,” per Ozempic’s web site.

RELATED: What You Should Know About Your Heart Health, Whatever Age You Are

The be aware is adopted by a disclaimer that “Ozempic® is not FDA approved for weight loss or chronic weight management” and that, right now, Novo Nordisk has not performed research to judge the impact on weight after discontinuation of the treatment.


The Bottom Line on Ozempic for Weight Loss


If you’re weighing the professionals and cons of making an attempt a drug like Ozempic, Dieter recommends continuing fastidiously: “For the average individual keen on weight loss, I’d advise caution. While Ozempic has delivered results in some cases, the side effects and the temporary nature of its effects (with weight often returning post-discontinuation) make it less ideal.”

If you resolve to ask your physician about it, Singh suggests utilizing it as “as an opportunity for your qualified healthcare provider to dive into your health to find some reasons why you may not be able to drop the weight on your own.”

RELATED: How to Set Realistic Weight-Loss Goals

Singh provides that for his sufferers, Ozempic and Wegovy have been game-changers for weight reduction — supplied that there are different way of life modifications in place: “Based on the results I have seen in my practice, they should absolutely be prescribed for weight loss. But with any weight loss medication, we see a rebound weight gain once the medication is stopped, if the addition of the medication is the only change the patient is making.”

Quintero, then again, doesn’t suppose that folks exterior of those that battle with weight problems and sort 2 diabetes must be utilizing the drug: “Ozempic should not be used by anyone who doesn’t have diabetes or obesity and whose motive is just to lose weight. This is because the weight loss achieved from Ozempic is temporary, and you will regain weight after discontinuing the drug. And if you keep using it long-term, it will certainly cause side effects.”

“Given the side effects and the nature of weight loss, it’s essential to consult a medical professional before considering its use,” notes Dieter. Remember that sustainable weight reduction comes out of your habits — not relying solely on treatment — so Ozempic isn’t a band-aid answer to keep away from altering your way of life. Whatever you do, don’t deal with Ozempic like an OTC drug which you could simply borrow from a buddy or purchase on-line.

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