We commonly hear about analysis involving hair development in rats, mice and macaques. However, I’ve by no means examine scientists managing to succesfully develop human hair in pigs. Until now.

Note that pig (porcine) skin has placing similarities to human pores and skin. Thanks to reader “Bryan” for first posting in regards to the under new research.

Hair growth in pigs.
Hair development in pigs from human dermal papilla cell injections. Source: Experimental Dermatology.

Hair Growth in Pigs from Human Dermal Papilla Cells

In April 2023, Epibiotech CEO Jong-Hyuk Sung co-wrote an interesting letter in Experimental Dermatology. It entails his workforce’s success in rising hair in pigs by way of the injection of human dermal papilla cells (hDPCs).

Note that Mr. Sung has revealed a number of important hair related studies for greater than a decade. In November 2022, I coated his extremely fascinating at-the-time new abstract paper on efficient cell remedy for hair regeneration. He even responded to some reader feedback in that put up.

Hairy Pig
A furry pig rendition.

Coming again to this newest paper, the conclusion was that intradermal hDPC injections in pigs elevated the hair follicle quantity, thickness and angiogenesis. Moreover, a single injection of hDPCs appears to be efficient and survives for greater than 3 months in scientific research.

Key quote (barely reworded):

“Though numerous past research findings indicate the hair growth promoting effects of human DPCs in rodents, preclinical or clinical application alone has not been reported in pigs until now.”

The analysis workforce injected hDPCs into the backs of three pigs throughout six websites. After only one injection of hDPCs, hair follicle numbers elevated for 3 months. And hair follicle thickness was elevated for one month.

Interestingly, there was no distinction in hair follicle amount and thickness between low- and high-dose supply of human dermal papilla cells. Also of word, the variety of microvessels across the hair follicles was elevated within the hDPC-treated group.

Normally, I’d not write a complete put up for such a one-off animal mannequin research. However, two components made me rethink:

  1. The involvement of Epibiotech’s CEO within the analysis.
  2. Considering the truth that that is the primary ever report on dermal papilla injection spurred hair development in pigs.

Also of word, this analysis was funded by the South Korean authorities by way of the Korea Drug Development Fund and the Korean Fund for Regenerative Medicine. Yet extra motive to belief the legitimacy and reputability.

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